Benchmarking the ideal sample thickness in cryo-EM Michael W Martynowycz 1 2, Max T B Clabbers 2, Johan Unge 2, Johan Hattne 1 2, Tamir Gonen 3 2 4 The relationship between sample thickness and quality of data obtained is investigated by microcrystal…
#cryoEM #MicroED with electron counting. Protein structure at 0.8A resolution. Ab initio phasing for two proteins facilitated by electron counting on a falcon 4 direct electron detector. A section of…
MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP Michael W Martynowycz 1 2, Anna Shiriaeva 3 4, Xuanrui Ge 3 5, Johan Hattne 1 2, Brent L Nannenga 6 7, Vadim Cherezov 8 4, Tamir Gonen 9 2 10 Microcrystal electron diffraction (MicroED) is a…
The Gonen laboratory will hold the 6th MicroED course in 2020. The course will be held on Zoom on December 21, 2020 from 1 PM to 6 PM, eastern standard…
MicroED structure of lipid-embedded mammalian mitochondrial voltage-dependent anion channel Michael W. Martynowycz, Farha Khan, Johan Hattne, Jeff Abramson, and Tamir Gonen Microcrystal electron diffraction (MicroED) is an electron cryo-microscopy (cryo-EM)…
One of expected areas where MicroED may have an outstanding role is for proteins and complexes where crystal growth tend to yield smaller crystals only. Membrane proteins puts many challenges…