Center Collaborators

Driving Biomedical Projects (DBPs)

Institution	Project title	Investigator	Grant number
USC	Structure and function of opioid and cannabinoid receptors	Vadim Cherezov	R35GM127086, P01DA035764
UW	Design and structure of self assembling crystals	David Baker	R01AG063845
Caltech	Innovation by evolution: bringing new chemistry to life	Frances Arnold	R01GM138740
U Wisconsin	Design and structure of polymers	Samuel Gellman	R01GM061238
U Illinois	A scalable platform to discover antimicrobials of ribosomal origin	Wilfred van der Donk	R01AI144967
U Notre Dame	Chemical approaches to selectively target β-rich amyloids	Juan Del Valle	R01AG074570
UNL	Structural bases of tight junction form, function, and disruption	Alex J. Veccio	R35GM138368
Yale University	Structural investigation of rapafucins	Jun Liu	R01GM137319
Stanford	Structural investigation of GPCRs	Georgios Skiniotis	R01NS122394, R01GM083118
UCLA	Novel membrane permeable macrocycles	Patrick Harran	R21AI168952
UC Berkeley, Yale	Structural analysis of macrocycles containing embedded, atropisomeric pharmacophores	Alanna Schepartz (UC Berkeley), Scott Miller (Yale)	NSF CHE-2002182

Institution	Investigator	Project title
Duke	Robert Lefkowitz	Molecular regulation of cardiovascular 7-TM receptors
UVa/Miami	Mark Yeager	Structure analysis of viral assembly mechanisms
Notre Dame	Anthony Serianni	Identification of glucosidases
UCLA	Jeff Abramson	Functional and structural studies of unique pathogenic transporters in glycobiology
UC Berkeley	James Hurley	Structure of human ESCRT-I complex
Caltech	Pamela Bjorkman	Targeting the HIV reservoir using optimized anti-HIV antibodies
UCLA	Juli Feigon	Structure and function of human telomerase
CU Denver	Hongjin Zheng	Mechanistic studies of prokaryotic and eukaryotic nitrate/nitrite transport