Driving Biomedical Projects (DBPs)

InstitutionProject titleInvestigatorGrant number
USC Structure and function of opioid and cannabinoid receptors Vadim CherezovR35GM127086
UWDesign and structure of self assembling crystalsDavid BakerR01AG063845
CaltechInnovation by evolution: bringing new chemistry to lifeFrances ArnoldR01GM138740
U WisconsinDesign and structure of polymers Samuel GellmanR01GM061238
U Illinois A scalable platform to discover antimicrobials of ribosomal origin Wilfred van der DonkR01AI144967
U Notre DameChemical approaches to selectively target β-rich amyloidsJuan Del ValleR01AG074570
UNLStructural bases of tight junction form, function, and disruptionAlex J. VeccioR35GM138368
Yale UniversityStructural investigation of rapafucinsJun LiuR01GM137319
StanfordStructural investigation of GPCRsGeorgios SkiniotisR01NS122394
UCLANovel membrane permeable macrocyclesPatrick HarranR21AI168952

Completed projects

InstitutionInvestigatorProject title
DukeRobert LefkowitzMolecular regulation of cardiovascular 7-TM receptors
UVa/MiamiMark YeagerStructure analysis of viral assembly mechanisms
Notre DameAnthony SerianniIdentification of glucosidases
UCLA Jeff AbramsonFunctional and structural studies of unique pathogenic transporters in glycobiology
UC Berkeley James HurleyStructure of human ESCRT-I complex
Caltech Pamela BjorkmanTargeting the HIV reservoir using optimized anti-HIV antibodies
UCLA Juli FeigonStructure and function of human telomerase
CU DenverHongjin ZhengMechanistic studies of prokaryotic and eukaryotic nitrate/nitrite transport