Publications

Referencing us

MEDIC must be acknowledged in all publications that resulted from either collaboration with the Center or with individual personnel of the Center or utilized services of the Center. The NIH grant funding the MEDIC project is NIH/GM P41 136508.

As in all scientific publications, co-authorship for a member of the Scientific Staff is warranted when an individual has made a significant contribution to the scientific work being described.

Data policy

All data collected for structural purposes will be made publicly available upon publication. Structures will be deposited in the protein structure data bank (PDB) and the electron microscopy data bank (EMDB) prior to publication. All primary data associated with a structure will be made available to the community upon request.

Sharing of materials

All materials, plasmids, peptides, and protein fragments will be made available to the research community in accordance with NIH guidelines and in coordination with the UCLA technology development group (TDG) governing material transfer agreements (MTA).

Sharing of software and algorithms

All software and programs used for analysis or structure determination will be made available either as pseudocode or as standalone scripts/programs in accordance with NIH guidelines and in coordination with the UCLA technology development group (TDG) governing intellectual property dissemination and materials transfer agreements (MTA).

Publication list

Click the Altmetric or PlumX links to show article-level metrics. The MEDIC H-index = 6.

2021

Martynowycz, Michael W; Gonen, Tamir

Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED) Journal Article

In: STAR Protoc, vol. 2, no. 3, pp. 100686, 2021, ISSN: 2666-1667.

Abstract | Links | Altmetric

Danelius, Emma; Gonen, Tamir

Protein and Small Molecule Structure Determination by the Cryo-EM Method MicroED Journal Article

In: Methods Mol Biol, vol. 2305, pp. 323–342, 2021, ISSN: 1940-6029.

Abstract | Links | Altmetric

Martynowycz, Michael W; Gonen, Tamir

Studying Membrane Protein Structures by MicroED Journal Article

In: Methods Mol Biol, vol. 2302, pp. 137–151, 2021, ISSN: 1940-6029.

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Mu, Xuelang; Gillman, Cody; Nguyen, Chi; Gonen, Tamir

An Overview of Microcrystal Electron Diffraction (MicroED) Journal Article

In: Annu Rev Biochem, vol. 90, pp. 431–450, 2021, ISSN: 1545-4509.

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Martynowycz, Michael W; Gonen, Tamir

Ligand Incorporation into Protein Microcrystals for MicroED by On-Grid Soaking Journal Article

In: Structure, vol. 29, no. 1, pp. 88–95.e2, 2021, ISSN: 1878-4186.

Abstract | Links | Altmetric

Martynowycz, Michael W; Gonen, Tamir

Microcrystal Electron Diffraction of Small Molecules Journal Article

In: J Vis Exp, no. 169, 2021, ISSN: 1940-087X.

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Danelius, Emma; Halaby, Steve; van der Donk, Wilfred A; Gonen, Tamir

MicroED in natural product and small molecule research Journal Article

In: Nat Prod Rep, vol. 38, no. 3, pp. 423–431, 2021, ISSN: 1460-4752.

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Martynowycz, Michael W; Shiriaeva, Anna; Ge, Xuanrui; Hattne, Johan; Nannenga, Brent L; Cherezov, Vadim; Gonen, Tamir

MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP Journal Article

In: Proc Natl Acad Sci U S A, vol. 118, no. 36, 2021, ISSN: 1091-6490.

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Martynowycz, Michael W; Clabbers, Max T B; Unge, Johan; Hattne, Johan; Gonen, Tamir

Benchmarking the ideal sample thickness in cryo-EM Journal Article

In: Proc Natl Acad Sci U S A, vol. 118, no. 49, 2021, ISSN: 1091-6490.

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Lei, Hsiang-Ting; Mu, Xuelang; Hattne, Johan; Gonen, Tamir

A conformational change in the N terminus of SLC38A9 signals mTORC1 activation Journal Article

In: Structure, vol. 29, no. 5, pp. 426–432.e8, 2021, ISSN: 1878-4186.

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2020

Richards, Logan S; Millán, Claudia; Miao, Jennifer; Martynowycz, Michael W; Sawaya, Michael R; Gonen, Tamir; Borges, Rafael J; Usón, Isabel; Rodriguez, Jose A

Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER Journal Article

In: Acta Crystallogr D Struct Biol, vol. 76, no. Pt 8, pp. 703–712, 2020, ISSN: 2059-7983.

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Nguyen, Chi; Gonen, Tamir

Beyond protein structure determination with MicroED Journal Article

In: Curr Opin Struct Biol, vol. 64, pp. 51–58, 2020, ISSN: 1879-033X.

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Martynowycz, Michael W; Hattne, Johan; Gonen, Tamir

Experimental Phasing of MicroED Data Using Radiation Damage Journal Article

In: Structure, vol. 28, no. 4, pp. 458–464.e2, 2020, ISSN: 1878-4186.

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Martynowycz, Michael W; Khan, Farha; Hattne, Johan; Abramson, Jeff; Gonen, Tamir

MicroED structure of lipid-embedded mammalian mitochondrial voltage-dependent anion channel Journal Article

In: Proc Natl Acad Sci U S A, vol. 117, no. 51, pp. 32380–32385, 2020, ISSN: 1091-6490.

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Zhu, Lan; Bu, Guanhong; Jing, Liang; Shi, Dan; Lee, Ming-Yue; Gonen, Tamir; Liu, Wei; Nannenga, Brent L

Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED Journal Article

In: Structure, vol. 28, no. 10, pp. 1149–1159.e4, 2020, ISSN: 1878-4186.

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