The Special Projects Group at NYSBC performs fee-for-service structure determination and protein production, and also works closely with the NMR Department and the Simons Electron Microscopy Center.   If you have a specific inquiry concerning your scientific interests, please contact us.

• High Throughput Gene-To-Structure Services
  • Gene construct design and cloning
  • Protein expression and purification
  • Crystallization and structure determination
• Structure-Based Drug Discovery
  • High throughput small molecule screening
  • Protein-small molecule complex structure
  • Protein-antibody complex structure
• X-Ray Crystallography
  • Crystallization of protein samples
  • Sample testing and data collection
  • High resolution data collection
  • Data analysis and structure determination
• NMR Protein Characterization
  • Structure determination of proteins, nucleic acids and complexes
  • Characterization of protein dynamics
  • Membrane protein structure determination
  • In-cell NMR
• Protein Production
  • Bacterial, insect or mammalian cell expression
  • Protein purification
  • Membrane proteins